Oral general anesthetics and metabolitically resistant...

Details Oral general anesthetics and metabolitically resistant... Oral general anesthetics and metabolitically resistant...

2006-04-11

2006-04-11

Kumar, Shailendra (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S212030, C514S386000, C514S418000, C514S730000

Reexamination Certificate

active

07026358

ABSTRACT:
The present invention is directed to novel themisone derivative compounds that have been modified to prevent the formation of the toxic metabolite, 2-phenyl-acrylamide. Compositions comprising such derivative compounds have activity as anesthetics and as neuroprotective agents.

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Dale, J. A., Dull, D. L. and Mosher, H. S. (1969). “Alpha Methoxy-alpha-trifluoromethylphenylacetic Acid, a Versatile Reagent for the Determination of Enantiomeric Composition of Alcohols and Amines”. Journal of Organic Chemistry vol. 34, No. 9 pp. 2543-2549.
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