Metal catalysts and methods for making and using same

Details Metal catalysts and methods for making and using same Metal catalysts and methods for making and using same

2006-09-19

2006-09-19

Nazario-Gonzalez, Porfirio (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S403000, C548S523000, C548S524000, C549S355000, C549S429000, C549S510000, C556S136000, C556S466000, C562S433000, C562S553000, C562S590000, C564S336000, C564S340000, C502S166000, C502S167000

Reexamination Certificate

active

07109343

ABSTRACT:
Compounds having the formula:are disclosed. M1and M2are the same or different and are transition metal atoms or ions; Z2and Z3, independently, are the atoms necessary to complete a 3–12 membered heterocyclic ring; Z1is an alkylene or arylene group; Q1and Q2are the same or different and are electron withdrawing groups; L1and L3, taken together, represent —O—CR13—O—; L2and L4, taken together, represent —O—CR14—O—; and R13and R14are the same or different and are selected from the group consisting of alkyl groups and aryl groups or R13and R14represent alkylene or arylene groups that are directly or indirectly bonded to one another. Methods for making such compounds are also disclosed, as are intermediates which can be used in their preparation. Also disclosed are methods for carrying out C—H insertion reactions using bis-transition metal catalysts, such as the above compounds. Procedures for preparing d-threo methylphenidate, tolterodine, CDP-840, nominfensine, and sertraline, are described.

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