Use of diazepines for preparing medicines for treating...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S555000

Reexamination Certificate

active

07015213

ABSTRACT:
The invention concerns the use of pyrido-thieno-triazolo-diazepins for preparing a medicine for treating pathological conditions or diseases involving one of the growth hormone release inhibiting factor receptors. The invention also concerns novel pyrido-thieno-triazolo-diazepins and therapeutic compositions containing them.

REFERENCES:
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patent: 2 660 311 (1991-10-01), None
CAPLUS printout of Prunonosa et al., Determnation of the Anti-Platelet-Activating Factor BN-50727 and Metabolites in Human Urine by High-Performance Liquid Chromatography Using Solid-Phase Extraction, J. Chromatogr., B: Biomed. Appl., vol. 677, No. 2, pp. 388-392, 1996.
CAPLUS printout of Girault et al., Simultaneous Quantitative Measurement of a New Platelet Activating Factor Antagonist (BN 50730) and its Two Main Metabolites in Human Plasma and Urine by LC-MS, Chromatographia, vol. 39, No. 3-4, pp. 228-238, 1994.
CAPLUS printout of Miyazawa et al., Structure-Activity Studies on Triazolothienodiazepine Derivatives as Platelet-Activating Factor Antagonists, Chem. Pharm. Bull., vol. 39, No. 12, pp. 3215-3220, 1991.
Yang, L., Non-Peptide Somatostatin Receptor Ligands, Annual Reports In Medicinal Chemistry, vol. 34, pp. 209-218, 1999.
Doly et al, “Prevention . . . BN 50730”, Ophthalmic Research, vol. 25, 1993, pp. 314-318.
Rabinovici et al, “Platelet . . . Antagonist”, Journal of Pharmacology and Experimental Therapeutics, vol. 225, No. 1, 1990, pp. 256-263.

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