Pyrrolo[2,1-c][1,4] benzodiazepines compounds and process...

Details Pyrrolo[2,1-c][1,4] benzodiazepines compounds and process... Pyrrolo[2,1-c][1,4] benzodiazepines compounds and process...

2006-03-21

2006-03-21

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S496000

Reexamination Certificate

active

07015215

ABSTRACT:
The present invention provides Analogues of 1,1′-{[(bisalkane-1,N-diyl)piperazine]dioxy}bis(11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one] of formula (VI)where n=2 to 10; a pharmaceutical composition comprising the above analogs and a process of preparing these analogues.

REFERENCES:
S. Kunimoto et al., The Journal of Antibiotics, 1980, vol. XXXIII, No. 6, pp. 665-667.
D. Kaplan et al., Biochemistry, 1981, vol. 20, pp. 7572-7580.
D. Thurston et al., J. Org. Chem., 1996, vol. 61, pp. 8141-8147.

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