Delivery of a therapeutic agent in a formulation for reduced...

Details Delivery of a therapeutic agent in a formulation for reduced... Delivery of a therapeutic agent in a formulation for reduced...

2006-01-03

2006-01-03

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S023000, C514S034000, C514S256000, C514S974000

Reexamination Certificate

active

06982255

ABSTRACT:
Methods and compositions for reducing toxicity of a toxic agent are provided in which a polysaccharide, galactomannan is coadministered with a therapeutic agent in a liquid formulation to a subject to reduce toxicity of the agent for the subject.

REFERENCES:
patent: 5118673 (1992-06-01), Carpenter et al.
patent: 5773425 (1998-06-01), McAnalley et al.
patent: 5786342 (1998-07-01), Carpenter et al.
patent: 5834442 (1998-11-01), Raz et al.
patent: 5861142 (1999-01-01), Schick
Ouchi et al., “Synthesis and Cytotoxic Activity of Oxidized Galactomannan/ADR Conjugate”, J.M.S. Pure Applied Chemistry, 1997, A34(6), pp. 975-989.

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