Ortho-substituted anthranilic acid amides and their use as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S313000, C514S338000, C514S357000, C514S252030, C544S235000, C546S159000, C546S283100, C546S275700, C546S330000, C546S337000

Reexamination Certificate

active

07081468

ABSTRACT:
Ortho-substituted anthranilic acid amides and use thereof as pharmaceutical agents for treating diseases that are triggered by persistent angiogenesis are described.

REFERENCES:
patent: 6448277 (2002-09-01), Altmann et al.
patent: WO 0027819 (2000-05-01), None
patent: WO 0027820 (2000-05-01), None
Strandtmann et al, J. Med. Chem. (1967), 10(6):1063-1065.
Sofina et al. Experimental Evaluation of Antitumor Drugs in the USA and USSR and Clinical Correlations. NCI Monograph 55. NIH Publication No. 80-1933 (1980).
Augustin, “Antiangiogenic tumour therapy: will it work?”Trends in Pharmacological Sciences, Elsevier Trends Journal, vol. 19, No. 6, Jun. 1, 1998, pp. 216-222, XP004145666.

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