Autonomic nervous system testing by bi-variate spectral analysis

Details Autonomic nervous system testing by bi-variate spectral analysis Autonomic nervous system testing by bi-variate spectral analysis

1994-02-22

1995-05-30

Kamm, William E.

Surgery

Truss

Pad

A61B 50452

Patent

active

054193389

ABSTRACT:
Apparatus and method for testing the autonomic nervous system of a mammal through bi-variate analysis of heart period (RR) and QT interval variability obtained through data processing of electrocardiographic data. The method and apparatus enables both the parasympathetic and sympathetic controls on the heart to be evaluated for imbalances therebetween, which may indicate a predisposition for sudden cardiac death.

REFERENCES:
"What is Heart Spectrum Rate Analysis?", Medic Monitor News, vol. 2, No. 2, Fall 1993.
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J. Sarma et al., PACE, vol. 10, 485-491 (1987).
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J. Sarma et al., Br. Heart J., 60:434-439 (1988).
J. Sarma et al., Am. J. Cardiol., 54:103-108 (1984).
Sarma et al., "Circadian and Power Spectral Changes in Heart Rate and QT Interval During Acute Hypothyroidism: Possible Antiarrhythmic Mechanisms", PACE, vol. 16, Pt. II, Abstract No. 120, p. 879 (1993).
J. Sarma, "Circadian and Spectral Changes of RR and QT", Am. J. Cardiology, In Press (1994).
M. Antimisiaris et al., "Effects of Amiodarone on the Circadian Rhythm and Power Spectral Changes of Heart Rate and QT Interval", American Heart Journal, In Press (1994).
J. Sarm et al., Am. J. Cardiol., 66:959-963 (1990).
J. Sarma et al., "The Concept of Corrected QT Interval", Ch. 3 in Clinical Aspects of Ventricular Repolarization, ed. G. Butrous et al., Farrand Press (London 1989).
J. Sarma et al., "Circadian Rhythmicity of Heart Rate and Myocardial Repolarization", Ch. 31 in Electropharmacological Control of Cardiac Arrhythmias, eds. Singh et al., Futura Publ. Co. Inc. (Mount Kisco 1994).

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