Microfluidic devices and methods for two-dimensional...

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

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C204S605000

Reexamination Certificate

active

07041208

ABSTRACT:
A microfluidic device includes first and second substrates and a microfluidic cavity formed in one of the first and second substrates. The microfluidic cavity has a width (W) and a depth (D), wherein the other of the first and second substrates encloses the microfluidic cavity and a width (W) to depth (D) ratio is at least 100 with the depth (D) being from about 10 μm to about 150 μm. The device also includes a plurality of ports formed in the other of the first and second substrates to permit access to the microfluidic cavity and a third substrate disposed on the second substrate and including microchannels formed therein. The microchannels are formed so that a plurality of ports formed in the second substrate for sample selection and sample output communicate therewith.

REFERENCES:
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patent: 6136171 (2000-10-01), Frazier et al.
patent: 6169394 (2001-01-01), Frazier et al.
patent: 6221654 (2001-04-01), Quake et al.
patent: 6268219 (2001-07-01), Mcbride et al.
patent: 6321791 (2001-11-01), Chow
patent: 6475363 (2002-11-01), Ramsey
patent: 2762639 (1998-03-01), None
patent: 11-273044 (1999-10-01), None
International Search Report for PCT/US02/39617.

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