Antibodies to human oncogene induced secreted protein I

Details Antibodies to human oncogene induced secreted protein I Antibodies to human oncogene induced secreted protein I

2006-09-19

2006-09-19

Nolan, Patrick J. (Department: 1644)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

C530S388220, C530S387700, C424S139100, C424S141100, C424S144100, C424S155100, C435S007100

Reexamination Certificate

active

07109306

ABSTRACT:
The present invention relates to a novel protein, the Human Oncogene Induced Secreted Protein I (“HOIPS I”) protein. In particular, isolated nucleic acid molecules are provided encoding the human HOIPS I protein. HOIPS I polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Antibodies to human HOIPS I are also provided, as are diagnostic methods for detecting abnormal cell proliferation and differentiation disorders and therapeutic methods for treating the same.

REFERENCES:
patent: 2002/0086364 (2002-07-01), Honjo
patent: WO-91/00292 (1991-01-01), None
patent: WO-99/18205 (1999-04-01), None
patent: WO-00/01817 (2000-01-01), None
Janeway et al. Immunobiology, Third edition (1999), Garland Publishing Inc, 1:6, 2:17-2:18, and 3:2-3:5.
Colman, P.M. “Effects of amino acid sequence changes on nantibody-antigen interactions” Research in Immunology, 1994, 145:33-36.
Begum, N.A. et al., “Human MD-1 Homologue is a BCG-Regulated Gene Product in Monocytes: Its Identification by Differential Display”, Biochem. Biophys. Res. Commun. 256:325-329, Academic Press, Inc. (1999).
Burk et al., “Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein,” EMBO J. 10:3713-3719, Oxford University Press (1991).
Nagai et al., “Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide”, Blood, 99(5):1699-1705 (2002).
Golay, J. et al., “A Single Point Mutation in the v-ets Oncogene Affects Both Erythroid and Myelomonocytic Cell Differentiation,” Cell 5:1147-1158, Cell Press (1988).
Introna, M. et al., “Mutations in v-myb Alter the Differentiation of Myelomonocytic Cells Transformed by the Oncogene,” Cell 63:1287-1297, Cell Press (1990).
Klempnauer, K.-H. et al., “Subcellular Localization of Proteins Encoded by Oncogenes of Avian Myeloblastosis Virus and Avian Leukemia Virus E26 and by the Chicken c-myb Gene,” Cell 37:537-547, MIT (1984).
Miyake, K. et al., “Mouse MD-1, a Molecule That Is Physically Associated with RP105 and Positively Regulates Its Expression,” J. Immunol. 161:1348-1353, American Association of Immunologists (1998).
Moscovici et al., “Transformation of Hemopoietic Cells with Avian Leukemia Viruses,” in Advances in Viral Oncology, Klein, G., ed., Raven Press, New York, NY, pp. 83-106 (1982).
Ness, S.A. et al., “The v-myb Oncogene Product Binds to and Activates the Promyelocyte-Specific mim-1 Gene,” Cell 59:1115-1125, Cell Press (1989).
Queva, C. et al., “Expression patterns of c-myb and v-myb induced myeloid-1 (mim-1) gene during the development of the chick embryo,” Develop. 114:125-133 (1992).
Hillier et al., Genbank Accession No. T84854 (Mar. 1995).
Hillier et al., Genbank Accession No. T91708 (Mar. 1995).
Hillier et al., Genbank Accession No. T92475 (Mar. 1995).
Okubo, Genbank Accession No. C02431 (Jul. 1996).
Adams et al., Genbank Accession No. AA340310 (Apr. 1997).
NCI-CGAP, GenBank Accession No. AA688404 (Dec. 1997).
Hudson, GenBank Accession No. G26160 (Jun. 1996).
Chang et al., GenBank Accession No. R10399 (Apr. 1991).

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