Photodynamic treatment of targeted cells

Details Photodynamic treatment of targeted cells Photodynamic treatment of targeted cells

2006-03-28

2006-03-28

Gibson, Roy D. (Department: 3739)

Surgery: light, thermal, and electrical application

Light, thermal, and electrical application

Light application

C607S089000, C604S021000, C424S450000

Reexamination Certificate

active

07018395

ABSTRACT:
The present invention is drawn to methods for photodynamic therapy (PDT) of a target cell, target tissue or target composition in a mammalian subject, using a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. This targeted substance preferably selectively binds to the target cell, target tissue or target composition. Light at a wavelength or waveband corresponding to that which is absorbed by the targeted substance is then administered. The light intensity is relatively low, but a high total fluence is employed to ensure the activation of the targeted photosensitizing agent or targeted prodrug product.

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