Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-03-28
2006-03-28
Nazario-Gonzalez, Porfirio (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C549S204000, C562S402000, C562S466000
Reexamination Certificate
active
07019152
ABSTRACT:
The present invention relates to the field of organic synthesis and more particularly to a new process for the optical resolution of a precursor of sclareolide. This process includes the reaction of [(1RS,2RS,4aSR,8aSR)-2-hydroxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl]acetic acid, or an alkaline salt thereof, with an enantiomer of the 2-(methylamino)-1-phenyl-1-propanol, or an ammonium salt thereof respectively, which is used as resolving agent.
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Article, XP-002256238, Ephedrin, PD 00-00, pp. 1181-1182 (1997).
T Sukasa Koga et al. XP004143697“Resolution of sclareolide as a key intermediate for the synthesis of AmbrokR” Tetrahedron, Asymmetry, Elsevier Science Publishers, Amsterdam, NL, vol. 9, No. 21, pp. 3819-3823 (1998).
Firmenich SA
Nazario-Gonzalez Porfirio
Winston & Strawn LLP
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