Fused bicyclic pyridine derivatives as tachykinin receptor...

Details Fused bicyclic pyridine derivatives as tachykinin receptor... Fused bicyclic pyridine derivatives as tachykinin receptor...

2006-04-18

2006-04-18

Kifle, Bruck (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S234200, C514S302000, C540S455000, C540S490000

Reexamination Certificate

active

07030107

ABSTRACT:
A novel fused bicyclic pyridine derivative or a salt thereof that acts as a tachykinin receptor antagonist, in particular as an NK1 receptor antagonist, is represented by the following general formula (1):wherein the rings A and B are each a benzene ring which may have 1 to 3 substituents (any adjacent two of which may be bound to one another to form a ring);the ring C is a nitrogen-containing ring having a hydrogen atom substituted with a nitrogen atom;R1and R2are each independently a hydrogen atom, a C1to C6alkyl group, a C1to C6alkylsulfonyl group, a C1to C6alkylcarbonyl group, or a C1to C6alkoxycarbonyl group, or R1and R2are bound to one another to form the ring D; m is 1 or 2; n is 2 or 3; and q is an integer from 1 to 4.

REFERENCES:
patent: 6147071 (2000-11-01), Natsugari et al.
patent: 652218 (1995-05-01), None
patent: 97/24356 (1997-07-01), None

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