Method of screening a gene

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C536S024300, C536S024330

Reexamination Certificate

active

07052835

ABSTRACT:
The present invention provides a method of screening genes based on expression information differing from gene expression information obtainable by DNA chip/DNA microarray techniques. The method of screening genes comprises performing in situ hybridization in respect of a tissue or cell sample from an organism using a probe which specifically hybridizes with mRNA and/or expression sequence tag being a product of gene expression, and examining localization of the mRNA and/or expression sequence tag in the tissue or cell.

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Asai S. Analysis of Morphology by in situ Hybridization following Genome Wide Screening. 73rdJapanese Biochemistry Society Annual Meeting [in Japanese] (with Applicants' English translation/explanation). Oct. 13, 2000.
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Asai S. et al. Acute Ischemic Change of mRNA Expression in the Hippocampus by GeneChip Array Analysis: A Starting Point for Post-Genome Strategy. 74thJapanese Pharmacological Society Annual Meeting. Mar. 21, 2001.

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