Methods and compositions utilizing quinazolinones

Details Methods and compositions utilizing quinazolinones Methods and compositions utilizing quinazolinones

2006-09-12

2006-09-12

Raymond, Richard L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C544S287000

Reexamination Certificate

active

07105668

ABSTRACT:
Quinazolinones of formulae 1a, 1b, 1cand 1dare disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.

REFERENCES:
patent: 3320124 (1967-05-01), Waletzky et al.
patent: 3322756 (1967-05-01), Ruschig et al.
patent: 3723432 (1973-03-01), Ott
patent: 3740442 (1973-06-01), Ott et al.
patent: 3925548 (1975-12-01), Oh
patent: 3962244 (1976-06-01), Weyer et al.
patent: 4281127 (1981-07-01), LeMahieu et al.
patent: 4729996 (1988-03-01), Wright et al.
patent: 4734419 (1988-03-01), Hashimoto et al.
patent: 4808590 (1989-02-01), Higa et al.
patent: 4857530 (1989-08-01), Berman et al.
patent: 4859670 (1989-08-01), Kampe et al.
patent: 4866084 (1989-09-01), Gunasekera et al.
patent: 4970226 (1990-11-01), Sun et al.
patent: 4981856 (1991-01-01), Hughes
patent: 4992550 (1991-02-01), Hughes
patent: 5037829 (1991-08-01), Freyne et al.
patent: 5081124 (1992-01-01), Hughes
patent: 5147875 (1992-09-01), Coates et al.
patent: 5187167 (1993-02-01), Hughes
patent: 5204354 (1993-04-01), Chakravarty et al.
patent: 5264439 (1993-11-01), Greenlee et al.
patent: 5280027 (1994-01-01), Andrew et al.
patent: 5316906 (1994-05-01), Haugland et al.
patent: 5330987 (1994-07-01), Allen et al.
patent: 5342944 (1994-08-01), Mohan et al.
patent: 5430148 (1995-07-01), Webber et al.
patent: 5444061 (1995-08-01), Bisset et al.
patent: 5449678 (1995-09-01), Pines et al.
patent: 5470878 (1995-11-01), Michnick et al.
patent: 5561133 (1996-10-01), Bisset et al.
patent: 5574057 (1996-11-01), Ireland et al.
patent: 5707992 (1998-01-01), Webber et al.
patent: 5714493 (1998-02-01), Myers et al.
patent: 5747498 (1998-05-01), Schnur et al.
patent: 5753664 (1998-05-01), Aono et al.
patent: 5756450 (1998-05-01), Hahn et al.
patent: 5756502 (1998-05-01), Padia et al.
patent: 5756510 (1998-05-01), Griffin et al.
patent: 5770595 (1998-06-01), Klein et al.
patent: 5773476 (1998-06-01), Chen et al.
patent: 5777115 (1998-07-01), Leigh et al.
patent: 5780476 (1998-07-01), Underiner et al.
patent: 5783577 (1998-07-01), Houghten et al.
patent: 5789427 (1998-08-01), Chen et al.
patent: 5795898 (1998-08-01), Brown et al.
patent: 5801181 (1998-09-01), Michnick et al.
patent: 5801182 (1998-09-01), Klein et al.
patent: 5804584 (1998-09-01), Underiner et al.
patent: 5807861 (1998-09-01), Klein et al.
patent: 5807862 (1998-09-01), Klein et al.
patent: 5811429 (1998-09-01), Connell et al.
patent: 5817662 (1998-10-01), Klein et al.
patent: 5837703 (1998-11-01), Kumar et al.
patent: 5852024 (1998-12-01), Pines et al.
patent: 5859018 (1999-01-01), Brown et al.
patent: 5869665 (1999-02-01), Padia et al.
patent: 5885996 (1999-03-01), Webber et al.
patent: 5891879 (1999-04-01), Nagler et al.
patent: 5892114 (1999-04-01), Goldmann et al.
patent: 5922866 (1999-07-01), Miyata et al.
patent: 5929081 (1999-07-01), Brown et al.
patent: 5939421 (1999-08-01), Palanki et al.
patent: 5948775 (1999-09-01), Koko et al.
patent: 6008010 (1999-12-01), Greenberger et al.
patent: 6136812 (2000-10-01), Chenard et al.
patent: 6156758 (2000-12-01), Kung et al.
patent: 6207403 (2001-03-01), Goldstein et al.
patent: 6245768 (2001-06-01), He et al.
patent: 6518277 (2003-02-01), Sadhu et al.
patent: 6545004 (2003-04-01), Finer et al.
patent: 6545005 (2003-04-01), Baxter et al.
patent: 6559160 (2003-05-01), Schall et al.
patent: 6562831 (2003-05-01), Finer et al.
patent: 6613798 (2003-09-01), Porter et al.
patent: 6627755 (2003-09-01), Chenard et al.
patent: 6630479 (2003-10-01), Finer et al.
patent: 6753428 (2004-06-01), Bergnes et al.
patent: 6794379 (2004-09-01), Medina et al.
patent: 6831085 (2004-12-01), Bergnes et al.
patent: 2001/0046997 (2001-11-01), Abraham et al.
patent: 2002/0165221 (2002-11-01), Baxter et al.
patent: 2002/0169159 (2002-11-01), Medina et al.
patent: 2002/0198326 (2002-12-01), Aoyama et al.
patent: 2003/0055054 (2003-03-01), Medina et al.
patent: 2003/0119854 (2003-06-01), Schall et al.
patent: 2003/0139457 (2003-07-01), Baxter et al.
patent: 2003/0195211 (2003-10-01), Sadhu et al.
patent: 2004/0023996 (2004-02-01), Finer et al.
patent: 2004/0048853 (2004-03-01), Bergnes
patent: 2004/0067969 (2004-04-01), Bergnes et al.
patent: 2004/0077662 (2004-04-01), Zhou et al.
patent: 2004/0077667 (2004-04-01), Matsuoka et al.
patent: 2004/0077668 (2004-04-01), Feng et al.
patent: 2004/0082567 (2004-04-01), McDonald et al.
patent: 2004/0116438 (2004-06-01), Luet al.
patent: 2004/0142949 (2004-07-01), Bergnes et al.
patent: 2004/0192913 (2004-09-01), Bergnes et al.
patent: B-12617/88 (1988-09-01), None
patent: 3721855 (1988-09-01), None
patent: 056637 (1982-01-01), None
patent: 0056637 (1982-07-01), None
patent: 0 286 813 (1988-02-01), None
patent: 0 286 813 (1988-02-01), None
patent: 0 341 990 (1989-11-01), None
patent: 0 341 990 (1989-11-01), None
patent: 0360417 (1990-03-01), None
patent: 0360417 (1990-03-01), None
patent: 0 373 891 (1990-06-01), None
patent: 0 481 614 (1992-04-01), None
patent: 0 509 643 (1992-10-01), None
patent: 0 512 676 (1992-11-01), None
patent: 0 534 706 (1993-03-01), None
patent: 0884310 (1998-12-01), None
patent: 0884316 (1998-12-01), None
patent: 0884319 (1998-12-01), None
patent: 0884319 (1998-12-01), None
patent: 900S68 (1999-03-01), None
patent: 0903344 (1999-03-01), None
patent: 1 072 952 (2000-01-01), None
patent: 1 174 430 (2002-01-01), None
patent: 2271111 (1994-04-01), None
patent: 184797 (1984-10-01), None
patent: 62-138473 (1987-06-01), None
patent: 06049070 (1994-02-01), None
patent: WO 91/12001 (1991-08-01), None
patent: WO 93/11115 (1993-06-01), None
patent: WO 93/19051 (1993-09-01), None
patent: WO 93/20055 (1993-10-01), None
patent: WO 93/23404 (1993-11-01), None
patent: WO 94/21259 (1994-09-01), None
patent: WO 95/16682 (1995-06-01), None
patent: WO 95/19169 (1995-07-01), None
patent: WO95/24379 (1995-09-01), None
patent: WO96/06616 (1996-03-01), None
patent: WO 96/19224 (1996-06-01), None
patent: WO 96/28430 (1996-09-01), None
patent: WO 96/28444 (1996-09-01), None
patent: WO 96/39403 (1996-12-01), None
patent: WO 9710221 (1997-03-01), None
patent: WO 97/43276 (1997-11-01), None
patent: WO 98/26664 (1998-06-01), None
patent: WO 98/29410 (1998-07-01), None
patent: WO 98/34613 (1998-08-01), None
patent: WO 98/58947 (1998-12-01), None
patent: WO 99/08501 (1999-02-01), None
patent: WO 00/00491 (2000-01-01), None
patent: WO00/07017 (2000-02-01), None
patent: WO 01/74344 (2000-10-01), None
patent: WO 00/69827 (2000-11-01), None
patent: WO 01/16114 (2001-03-01), None
patent: WO 01/19800 (2001-03-01), None
patent: WO 01/23364 (2001-04-01), None
patent: WO 01/23365 (2001-04-01), None
patent: WO 01/25235 (2001-04-01), None
patent: WO 01/30768 (2001-05-01), None
patent: WO 01/42216 (2001-06-01), None
patent: WO 01/52234 (2001-07-01), None
patent: WO 01/66519 (2001-09-01), None
patent: WO 01/70737 (2001-09-01), None
patent: WO 01/81346 (2001-11-01), None
patent: WO 01/95884 (2001-12-01), None
patent: WO 02/14319 (2002-02-01), None
patent: WO 03/027234 (2003-04-01), None
patent: WO 03/043995 (2003-05-01), None
patent: WO 03/070701 (2003-08-01), None
patent: WO 03/070701 (2003-08-01), None
patent: WO 03/079973 (2003-10-01), None
patent: WO 03/094839 (2003-11-01), None
patent: WO 03/097053 (2003-11-01), None
patent: WO 03/099211 (2003-12-01), None
patent: WO 03/103575 (2003-12-01), None
patent: WO 03/105855 (2003-12-01), None
patent: WO 03/106417 (2003-12-01), None
patent: WO 03/106426 (2003-12-01), None
patent: WO 2004/004652 (2004-01-01), None
patent: WO 2004/018058 (2004-03-01), None
patent: WO 2004/009036 (2004-04-01), None
patent: WO 2004/034972 (2004-04-01), None
patent: WO 2004/039774 (2004-05-01), None
patent: WO 2004/064741 (2004-08-01), None
Alger et al., Chem. Abstract, 1977, vol. 86, Abstract No. 83505, p. 379.
Bergman et al., “Synthesis of Chrysogine, a Metabolite ofPenicillium chrysogenumand some related 2-substituted 4-(3H)-Quinazolinones”, 1990, Tetrahedron, vol. 46, pp. 1295-1310.
Chaurasia et al., Chem Abstract, 1982, Vol 96, Abstract No. 6681.
Tani et a., Chem Abstract 1980, vol. 93, Abstract No. 26374.
El-Nasser Ossman et al., Ch

Affiliated with

Also associated with

Rating

Methods and compositions utilizing quinazolinones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and compositions utilizing quinazolinones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions utilizing quinazolinones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3540182