Pharmaceutical formulations comprising labdanes for the...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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C424S725000, C514S451000, C514S732000

Reissue Patent

active

RE039061

ABSTRACT:
The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-ene-8α, 15-diol and/or derivatives thereof; b) labd-14-ene-8, 13-diol or derivatives thereof; c) 3β-hydroxy-labd-14-ene-8, 13-epoxy and/or derivatives thereof, d) a plant extract containing the aforementioned labdanes or derivatives thereof. The compositions of the invention exhibit cytotoxicity against cancerous cells and are utilized for the treatment of tumors and leukemias.

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