Process for carbapenem synthesis

Details Process for carbapenem synthesis Process for carbapenem synthesis

2006-07-04

2006-07-04

Berch, Mark L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07071330

ABSTRACT:
A process for synthesizing a compound represented by formula I:or a pharmaceutically acceptable salt thereof, wherein deprotection is conducted using a prereduced metal catalyst is disclosed.

REFERENCES:
patent: 3897424 (1975-07-01), Koppel et al.
patent: 3925372 (1975-12-01), Chauvette
patent: 3985737 (1976-10-01), Spitzer
patent: 3985746 (1976-10-01), Koster et al.
patent: 3992377 (1976-11-01), Chauvette et al.
patent: 3994885 (1976-11-01), Koppel
patent: 4001226 (1977-01-01), Spry
patent: 4217453 (1980-08-01), Christensen et al.
patent: 4269772 (1981-05-01), Melillo et al.
patent: 4299954 (1981-11-01), Spry
patent: 4369187 (1983-01-01), Christensen et al.
patent: 4383946 (1983-05-01), Christensen et al.
patent: 4414155 (1983-11-01), Liu et al.
patent: 4501741 (1985-02-01), Graves et al.
patent: 4656263 (1987-04-01), Kellogg
patent: 4783453 (1988-11-01), Christensen et al.
patent: 5034384 (1991-07-01), Greenlee et al.
patent: 5478820 (1995-12-01), Betts et al.
patent: 5872250 (1999-02-01), Williams et al.
patent: 5952323 (1999-09-01), Zimmerman et al.
patent: 6063931 (2000-05-01), Brands et al.
patent: 6180783 (2001-01-01), Williams et al.
patent: 0 562855 (1993-09-01), None
patent: 01075488 (1989-03-01), None
patent: WO 974 5430 (1997-12-01), None
Kawamoto, J. Antibiotics (2001), 54(12) 1080-1092.
D.G. Melillo et al., “A Practical Synthesis of (±)-Thienamycin”, 1980, pp. 2783-27386, vol. 21, Tetrahedron Letters.
L. M. Fuentes et al., “Lewis Acid Mediated Condensation of Chiral Imide Enolates. A General Approach to the Synthesis of Chiral Carbapenem Precursors”, 1985, pp. 4675-4676, vol. 108, J. Am. Chemical Society.
C. Wentrup et al., “A Stereocontrolled Synthesis of (+)- Thienamycin”, 1980, pp. 6161, vol. 102, J. Am. Chemical Society.
S.M. Berge et al., “Pharmaceutical Salts”, J. Pharm. Sci., vol. 66(1): pp. 1-16(1997).

Affiliated with

Also associated with

Rating

Process for carbapenem synthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for carbapenem synthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for carbapenem synthesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3534542