Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-09-26
2006-09-26
Caputa, Anthony (Department: 1646)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S387300
Reexamination Certificate
active
07112657
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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Database Search, DNA sequence alignments [Blastin 2.1.3 (Apr. 1, 2001), NCBI] A1-A14.
Database Search, protein sequence alignments [Blastin 2.2.1 (Jul. 12, 2001), NCBI] B1-B6.
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Melkonyan, et al.,PNAS USA, 94(25):13636-13641 (1997).
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Ono, T. et al., “Broad Antiproliferative Effects of Benidipine on Cultured Human Mesangial Cells in Cell Cycle Phases,”American Journal of Nephrology, vol. 22, 2002, 581-586.
Pippin, J.W. et al., “Direct in vivo Inhibition of the Nuclear Cell Cycle Cascade in Experimental Mesangial Proliferative Glomerulonephritis with Roscovitine, a Novel Cyclin-dependent Kinase Antagonist,”J. Clin. Invest., vol. 100:(10), 1997, 2512-2520.
Goddard Audrey
Godowski Paul J.
Gurney Austin L.
Pan James
Wood William I.
Barnes Elizabeth M.
Caputa Anthony
Dreger Ginger R.
Genentech Inc.
Howard Zachary C.
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