Pyrimidine derivatives as corticotropin releasing factor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S252140, C514S269000, C544S122000, C544S296000, C544S298000

Reexamination Certificate

active

07112585

ABSTRACT:
The present invention relates to novel heterocyclic antagonists of Formula (I) and pharmaceutical compositions comprising said antagonists of the corticotropin releasing factor receptor (“CRF receptor”)useful for the treatment of depression, anxiety, affective disorders, feeding disorders, post-traumatic stress disorder, headache, drug addiction, inflammatory disorders, drug or alcohol withdrawal symptoms and other conditions the treatment of which can be effected by the antagonism of the CRF-1 receptor.

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McCarthy, J.R., et al., “Chapter 2. Recent Progress in Corticotropin-Releasing Factor Receptor Agents,” Annual Reports in Medicinal Chemistry, vol. 34, 1999, pp. 11-20.

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