Triazole derivatives useful in therapy

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

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06977302

ABSTRACT:
The invention provides compounds of formula I,in-line-formulae description="In-line Formulae" end="lead"?R1—OP(O)(OH)2  Iin-line-formulae description="In-line Formulae" end="tail"?wherein R1represents the non-hydroxy portion of a triazole antifungal compound of the type comprising a tertiary hydroxy group; or a pharmaceutically acceptable sat thereof.The compounds of the invention are useful in the treatment of fungal infections, and have good aqueous solubility.

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63-Pharmaceuticals, vol. 119, 1993, p. 525.
Maurin, et al. Int. J. Pharm., 1993, vol. 94, pp. 11-14.

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