Lavendamycin analogs and methods of making and using them

Details Lavendamycin analogs and methods of making and using them Lavendamycin analogs and methods of making and using them

1993-06-04

1996-06-11

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514254, 514255, 514256, 544238, 544333, 544361, 546 86, 546 87, C07D40104, C07D47104, A61K 3144, A61K 31495

Patent

active

055256112

ABSTRACT:
The invention provides lavendamycin analogs having the following formula: ##STR1## wherein X, Y and R.sup.1 through R.sup.9 are defined in the specification, and salts of these analogs. The invention also provides a method of making the lavendamycin analogs. The lavendamycin analogs have antitumor and antimicrobial activity.

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