Pharmaceutical preparations for the inhibition of herpes...

Details Pharmaceutical preparations for the inhibition of herpes... Pharmaceutical preparations for the inhibition of herpes...

2005-12-20

2005-12-20

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C435S015000

Reexamination Certificate

active

06977248

ABSTRACT:
Disclosed herein are polysaccharide preparations enriched in 3-OST-3 modified heparan sulfate. Also disclosed are methods of treating herpes simplex viral type-1 infection using the pharmaceutical preparations of the invention.

REFERENCES:
patent: 4465666 (1984-08-01), Lukas et al.
patent: WO 98/05341 (1998-02-01), None
patent: WO 98/42754 (1998-10-01), None
patent: WO 99/22005 (1999-05-01), None
Lindahl, U. et al “Evidence for a 3-O-sulfated D-glucosamine residue . . . ” (1980) PNAS vol. 77, No. 11, pp. 6551-6555.
Lycke, E. et al “Binding of herpes simplex virus to cellular heparan . . . ” J. Gen. Virol. (1991) vol. 72, pp. 1131-1137.

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