Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or...
Reexamination Certificate
2005-02-01
2005-02-01
Fox, David T. (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
C800S260000, C800S271000, C800S274000, C800S287000, C800S288000, C435S199000, C435S320100, C435S419000, C435S468000, C536S023200, C536S023700
Reexamination Certificate
active
06849776
ABSTRACT:
The invention is related to a method and a DNA construct for controlling transgene segregation in a sexually reproducing multicellular organism (SRMO), especially in such SRMOs which are susceptible of interbreeding with their cultured or wild-type relatives. The method and construct allows the farmer to reuse the transgenic crop without risk for escape of the transgene into the environment. The DNA construct is a recoverable block of function (RBF) system comprising at least one blocking construct (BC), and at least one means for recovering the blocked functions. The BC has a capacity of blocking at least one molecular or physiological function essential for the development and/or reproductive cycle of the SRMO. The BC is closely linked to the transgene of intereset (TGI). The blocked function is recoverable by an external treatment or intervention, which is optionally combined with one or more recovering constructs (RC). Different types of RBFs, including single, full, delayed, double, multiple and reversed delayed RBF are disclosed.
REFERENCES:
patent: 5689041 (1997-11-01), Mariani et al.
patent: 5880333 (1999-03-01), Goff et al.
patent: 94 03619 (1994-02-01), None
patent: WO 9730162 (1997-08-01), None
patent: 00 37660 (2000-06-01), None
Williams, M. Tibtech 13:344-349, Sep. 1995.*
Kriete et al. Plant Journal 9(6): 809-818, 1996.*
Viktor Kuvshinov, “Development of Transgenic Crops Protected from Insect Damage and Transgene Escape”,Academic Dissertation in Genetics, University of Helsinki, Finland, Mar. 16, 2001.
Harue Akasofu et al., “Nucleotide Sequence of the Gene for theVigna mungoSulfhydryl-endopeptidase (SH-EP)”,Nucleic Acids Research, 1990, vol. 18, No. 7, obtained from website http://srs6.ebi.ac.uk/srs6bin/cgi-bin/wgetz?-e+embl-id:VMSHEPGO on Oct. 25, 2001; p. 1892 of N.A.R.
Kuvshinov et al. 2001, Plant Science 160:517-522.
Kuvshinov et al. 1999. Plant Cell Reports 18:773-777.
Shevelev et al. 1997. FEBS Letters 404:148-152.
Kuvshinov et al. 2001. Plant Science 160:341-353.
Jonathan Gressel, “Tandem Constructs: Preventing The Rise Of Superweeds” Tibtech. vol. 17, pp. 361-366, Sep. 1999.
Abstract —Williams et al., “Maintenance of male-sterile plants”, U.S. Appl. No. 5,750,867, Date Issued May 12, 1998, only.
Abstract —De Greef et al., “Plants with modified flowers seeds or embryos”, U.S. Appl. No. 5,767,374, Date Issued Jun. 16, 1998, only.
Abstract —Fabijanski et al., “Molecular methods of hybrid seed production”, U.S. Appl. No. 6,013,859, Date Issued Jan. 11, 2000, only.
Abstract —Van Tunen et al., “Male-sterile plants, methods for obtaining male-sterile plants and recombinant DNA for use therein”, U.S. Appl. No. 6,005,167, Date Issued Dec. 21. 1999, only.
Abstract —Oliver et al., “Control of plant gene expression”, U.S. Appl. No. 5,723,765, Date Issued Mar. 3, 1998, only.
Abstract —Goff et al, “Control of gene expression in plants by receptor mediated transactivation in the presence of a chemical ligand” U.S. Appl. No. 5,880,333, Date Issued Mar. 9, 1999, only.
Abstract —Poovaiah et al., “Control of growth and development of potato plants”, U.S. Appl. No. 5,498,533, Date Issued Mar. 12, 1996, only.
Henry Daniel, “Molecular Strategies for Gene Containment In Transgenic Crops”,Nature Biotechnology, Jun. 2002, pp. 581-586, vol. 20.
Kanerva Anne
Koivu Kimmo
Kuvshinov Viktor
Pehu Eija
Dodds and Associates
Fox David T.
UniCrop Ltd
LandOfFree
Molecular control of transgene segregation and its escape by... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Molecular control of transgene segregation and its escape by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Molecular control of transgene segregation and its escape by... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3512712