Sid nucleic acids and polypeptides selected from a...

Details Sid nucleic acids and polypeptides selected from a... Sid nucleic acids and polypeptides selected from a...

2005-12-20

2005-12-20

Mosher, Mary E. (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C536S023720, C536S024320, C536S023400, C435S032000, C435S320100, C435S325000, C435S252300, C435S254100, C530S324000

Reexamination Certificate

active

06977144

ABSTRACT:
The present invention relates to nucleic acids encoding SID® polypeptides which bind selectively to a polypeptide encoded by a pathogenic strain of the hepatitis C virus, as well as to the SID® polypeptides which are encoded by said nucleic acids.The invention also concerns vectors comprising a nucleic acid encoding a SID® polypeptide as well as host cells transformed with such vectors.The invention is also directed to two-hybrid methods which make use of the nucleic acids encoding a SID® polypeptide selected from a pathogenic strain of the hepatitis C virus as well as to methods for selecting molecules which inhibit the binding between a SID® polypeptide and a polypeptide which specifically binds thereto.

REFERENCES:
patent: 1 018 558 (2000-07-01), None
patent: IB-96/05315 (1996-02-01), None
Yanagi et al (PNAS 94:8738-8743, 1997).
Lesburg et al (Nature Structure Biology 6:937-943, 1999).
Flajolet M, et al., “A genomic approach of the hepatitis C virus generates a protein interaction map”, Gene, vol. 242, No. 1-2, Jan. 25, 2001, pp. 369-379.

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