Hybrid polyketide synthases combining heterologous loading...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

Reexamination Certificate

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C435S320100, C435S252300, C435S252350, C435S471000, C435S183000, C536S023100, C536S023200, C536S023700

Reexamination Certificate

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06960453

ABSTRACT:
A hybrid type I polyketide synthase gene typically containing a starter module and a plurality of heterologous extender modules is used to synthesize novel polyketides. It is preferably under the control of a type II polypolyketide synthase promoter e.g. act I ofS. coelicolor.

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