Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems
Reexamination Certificate
2005-11-22
2005-11-22
Getzow, Scott M. (Department: 3762)
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical therapeutic systems
Reexamination Certificate
active
06968234
ABSTRACT:
An implantable medical device has a medical unit, such as a pacemaker lead, and a casing at least partially enclosing the medical unit. The casing is formed of a base polymer such as a polyurethane, a polyurethane copolymer, a fluoropolymer and a polyolefin or a silicone rubber. The casing has biologically active agents covalently bonded to the base polymer. The biologically active agents can be attached to the base polymer as surface active end groups. As an alternative, the biologically active may be attached to a backbone the base polymer. As yet a further alternative, the biologically active agents may be attached to surface modifying end groups, which are in turn attached to the base polymer. Examples of suitable biologically active agents are microbial peptide agents, detergents, non-steroidal anti-inflammatory drugs, cations, amine-containing organosilicones, diphosphonates, fatty acids and fatty acid salts.
REFERENCES:
patent: 5043278 (1991-08-01), Nagaoka et al.
patent: 5217493 (1993-06-01), Raad et al.
patent: 5322520 (1994-06-01), Milder
patent: 5498248 (1996-03-01), Milder
patent: 5589563 (1996-12-01), Ward et al.
patent: 5725817 (1998-03-01), Milder
patent: 5752941 (1998-05-01), Romano' et al.
patent: 5755758 (1998-05-01), Woloszko et al.
patent: 5834051 (1998-11-01), Woloszko et al.
patent: 5895563 (1999-04-01), Muranushi
patent: 5939576 (1999-08-01), Lichtenhan et al.
patent: 5945457 (1999-08-01), Plate et al.
patent: 6017334 (2000-01-01), Rawls
patent: 6033719 (2000-03-01), Keogh
patent: 6060000 (2000-05-01), Milder et al.
patent: 6167886 (2001-01-01), Engel et al.
patent: 6190407 (2001-02-01), Ogle et al.
patent: 6193752 (2001-02-01), Hildebrandt
patent: 6245056 (2001-06-01), Walker et al.
patent: 6267782 (2001-07-01), Ogle et al.
patent: 2001/0049422 (2001-12-01), Phaneuf et al.
patent: 2002/0022046 (2002-02-01), Tedeschi et al.
patent: WO 98/23306 (1998-06-01), None
patent: WO 02/085425 (2002-10-01), None
Crossley, G.H., “Cardiac Pacing Leads,” vol. 18, No. 1, p. 95-112 (Feb. 2000).
Saito, N. et al., “Photochemical Grafting of α-Propylsulphate-Poly(ethylene oxide) on Polyurethane Surfaces and Enhanced Antithrombogenic Potential,”Biomaterials, vol. 18, No. 17, p. 1195-1197 (1997).
An, Y. & Richard Friedman, “Concise Review of Mechanisms of Bacterial Adhesion to Biomaterial Surfaces”,J Biomed Mater Res, 43: pp 338-348, 1998.
Byrd et al., “Intravascular Extraction of problematic or Infected Permanent Pacemaker Leads”,Pacing and Clinical Electrophysiology, vol. 22, No. 9, pp. 1348-1357, Sep. 1999.
Wagener et al., “Chiral Polyolefins Bearing Amino Acids”,Macromolecules 34, 7920-7922, 2001.
Wagener et al., “Perfect Comb' ADMET Grafted Copolymers”,Macromolecules 34, 6845-6849, 2001.
Getzow Scott M.
Medtronic Inc.
Soldner Michael C.
Wolde-Michael Girma
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