Method of evaluating antifungal agent

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

Reexamination Certificate

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C435S004000, C435S007310, C435S029000, C435S030000, C435S039000, C435S040510, C435S040520

Reexamination Certificate

active

06929927

ABSTRACT:
A correct viable cell number of a microorganism in a biological tissue is measured by cultivating a fragment of the biological tissue such as skin infected with the microorganism and administered with an antimicrobial agent, in a medium containing a phospholipid, a nonionic surfactant, or both of the phospholipid and the nonionic surfactant.

REFERENCES:
patent: 5789191 (1998-08-01), Mayer et al.
patent: 0 504 763 (1992-09-01), None
patent: 06-189739 (1994-07-01), None
Walsh, T.J. et al. 1990. Effects of preventive, early, and late antifungal chemotherapy with fluconazole in different granulocytopenic models of experimental disseminated candidiasis. J. Infect. Dis. 161: 755-760.

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