Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-12-06
2005-12-06
Saeed, Kamal (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S335500
Reexamination Certificate
active
06972299
ABSTRACT:
This invention relates to a compound and the use of the compound of the formulawherein R1, R2, R3, R4and R5are as defined in the description, A signifies —CH═CH— or —C≡C—; and B signifieswherein R6to R26, X and Y are as defined in the specification or a pharmaceutically acceptable salt thereof, for use in pharmaceutical compositions for the treatment or prevention of mGluR5 receptor mediated disorders.
REFERENCES:
patent: 3303199 (1967-02-01), Doebel et al.
patent: 3341548 (1967-09-01), Hoffer
patent: 4352818 (1982-10-01), Hunkeler et al.
patent: 4711962 (1987-12-01), Leone-Bay
patent: 2035905 (1972-02-01), None
patent: 059 390 (1982-09-01), None
patent: WO 91/00277 (1991-01-01), None
patent: WO 99/02497 (1999-01-01), None
patent: WO 99/08678 (1999-02-01), None
patent: WO 01/016121 (2001-03-01), None
Sakamoto et al.,Chem. Pharm. Bull. ,vol. 35(2), pp. 823-828 (1987.
Robert D. Miller,Chem. Mater.,vol. 6(7), pp. 1023-1032 (1994).
Rapoport et al.,Environ. Health Perspect.,vol. 67, pp. 41-45 (1986).
Bond et al.,Synth, Commun.,vol. 19, pp. 2551-2566 (1989).
Sintas et al.,Journal of Labelled Compds.&Radiopharmaceuticals,vol. 39, pp. 677-684 (1997).
Hoffer et al.,J.Med. Chem.,vol. 17(9), pp. 1019-1020 (1974).
Ohpa etal.,Chem. Pharm. Bull.,vol. 42, pp. 1784-1790 (1994).
Kulkarni et al.,Aust. J. Chem.,vol. 40(8), pp. 1399-1413 (1987).
Vasileuskii et al.,Bull. Acad. Sci USSR Div. Chem. Sci.,pp. 626-628 (1983).
F.J. LaRonde et al.,Inorg. Chim. Acta,vol. 296 (1), pp. 208-221 (1999).
Shafiee et al.,J. Heterocyclic Chem.,vol. 33, pp. 671-673 (1996).
Shafiee et al.,J. Heterocyclic Chem.,vol. 35, pp. 607-610 (1998).
Ivanova et al.,Chem. Heterocycl. Comp.,vol. 36(2), pp. 262-264 (2000).
G. H. Wadsworth,J.Chem. Soc.,vol. 57, p. 11 (1890).
Cornforth and Cookson,J. Chem. Soc.,pp. 1085-1087 (1952).
W. Ross et al.,J. Med. Chem.,vol. 15(10), pp. 1035-1040 (1972).
Mutel Vincent
Peters Jens-Uwe
Wichmann Juergen
Hoffmann-La Roche Inc.
Johnston George W.
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
Saeed Kamal
LandOfFree
Phenylethynyl and styryl derivatives of imidazole and fused... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phenylethynyl and styryl derivatives of imidazole and fused..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenylethynyl and styryl derivatives of imidazole and fused... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3493908