House dust mite allergen, Der f VII, and uses therefor

Details House dust mite allergen, Der f VII, and uses therefor House dust mite allergen, Der f VII, and uses therefor

2005-06-14

2005-06-14

Duffy, Patricia A. (Department: 1645)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C435S252300, C435S254110, C435S257200, C536S023500

Reexamination Certificate

active

06905845

ABSTRACT:
Isolated nucleic acids encoding allergens of the speciesDermatophagoides pteronyssinusandDermatophagoides farinae,Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a peptide having a Der p VII activity and a predicted molecular weight of about 22, 177 daltons is described. A cDNA encoding a peptide having Der f VII activity is also described. The nucleic acid of the invention can be used as probes to detect the presence of Der p VII or Der f VII nucleotide acid in a sample or for the recombinant production of peptides having a Der p VII or Der f VII activity. Peptides having a Der p VII or Der f VII activity can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mite allergens.

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