Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-08-23
2005-08-23
Wilson, James O. (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S030000, C536S045000, C536S052000, C536S102000, C536S114000, C536S124000, C424S458000, C424S457000, C424S461000, C424S462000, C424S468000, C424S494000, C424S497000
Reexamination Certificate
active
06933380
ABSTRACT:
The present invention provides low-residual-solvent containing excipients with residual solvent less than <3000 ppm. Most of the excipients are required to first be modified to become more water absorbing such as by attaching a water absorbing radical, e.g., (—CH2COONa) to the carbinol groups (—CH2OH) of the excipients to form a —CH2—O—CH2COONa linkage. The linkage of the water-absorbing groups to e excipients improves the water absorbing property of the excipients, which facilitates the replacing residual solvent with water. The residual solvent can be extracted from the excipient by way of mixing with a solvent/water solution containing (1) about 75-95% (v/v) isopropanol and about 5-25% water (v/v); (2) about 65-95% acetone and about 5-35% water; and (3) about 60-85% methanol and about 15-40% water.
REFERENCES:
patent: 5478571 (1995-12-01), Gala et al.
patent: 5534555 (1996-07-01), Meggelaars et al.
patent: 5574150 (1996-11-01), Yaginuma et al.
patent: 5840329 (1998-11-01), Bai
patent: 5989589 (1999-11-01), Cartilier et al.
patent: 6063402 (2000-05-01), Gebert et al.
patent: 6075177 (2000-06-01), Bahia et al.
patent: 6187339 (2001-02-01), de Haan et al.
patent: 6217909 (2001-04-01), Sherwood et al.
patent: 6271278 (2001-08-01), Park et al.
Huang Yun-Peng
Lee Fangchan
Shaw Jer-Yen
Bingham & McCutchen LLP
Chao Fei-Fei
Lewis Patrick
Wilson James O.
Yung-Zip Chemical Ind. Co., Ltd.
LandOfFree
Excipients containing low residual solvent and method for... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Excipients containing low residual solvent and method for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Excipients containing low residual solvent and method for... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3490232