Method for detection of fibrin clots

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S001130, C424S001650, C424S001810, C424S009100, C424S009300

Reexamination Certificate

active

06977068

ABSTRACT:
A method for the detection of fibrin in a source, in particular the in vivo detection of a fibrin in a patient, the method comprising supplying to the source or patient an amount of a detectable reagent comprising a plurality of discrete particles, each of the particles comprising a plurality of layers of carbon and being capable of binding to fibrin; and detecting the presence of the particles in the source. The particles may also comprise a detectable marker encased in said plurality of layers of carbon, the presence of said marker being capable of detection in said source.

REFERENCES:
patent: 5064634 (1991-11-01), Burch
patent: 5217705 (1993-06-01), Reno et al.
patent: 5228444 (1993-07-01), Burch
patent: 5330768 (1994-07-01), Park et al.
patent: 5640705 (1997-06-01), Koruga
patent: 5952321 (1999-09-01), Doherty et al.
patent: 6110204 (2000-08-01), Lazarov et al.
patent: B-48324 (1989-10-01), None
patent: 93/15768 (1993-08-01), None
patent: WO 99/04826 (1999-02-01), None
Bonnin et al. “Complementarity of Lung Scintigraphy and D-Dimer Test in Pulmonary Embolism”. European Jn. of Nuc. Med., (Apr. 1997) 24(4), 444-7.
Burch et al. “Technegas-a New Ventilation Agent for Lung Scanning”, Nuc. Med. Commun. (1986), 7(12), 365-71.
Senden et al. “The Physical and Chemical Nature of Technegas”, Jn. of Nuc. Med. (1997) vol. 38, No. 8, pp. 1327-1333.
The Handbook of Cosmetic Science and Technology, 1stEdition 1993, Elservier Advanced Technology.
Penfold et al, “Adsorption of Nonionic Surfactants on Silica Sol Particles: The Effects of Sol Type and Concentration Surfactant Type, Concentration, and Temperature”. Jm of Physical Chemistry (1996), 100(46), 18133-18137.
Pierson, H.O. The Handbook of Carbon, Graphite, Diamond, and Fullerenes. William Andrew Publishing/Noyes, 1993.
Chinger et al. (1987) “Haemocompatibility and biological course of carbonaceous composites for cardiovascular devices”Biomaterials 8:18-23.
Eriksson et al. (1997) “The initial reactions of graphite and gold with blood”J. Biomed. Mater. Res.37:130-136.
Rudee et al. (1980) “The Interaction of Blood with Amorphous Carbon” Proceedings, Thirty-eighth Annual Meeting Electron Microscopy Society of America, Aug., 1980, San Francisco, CA, (ed. G.W. Bailey) pps. 584-585.
Ginsberg, J.S. et al., “Evaluation of a soluble fibrin assay in patients with a suspected deep vein thrombosis,”Thrombosis and Haemostasis(1995) 74(3):833-836.
Nozaki, T. et al., “Production of fine aerosols labeled with various radionuclides by sublimation from a graphite boat, and their properties and tracer use,”Applied Radiation and Isotopes, Pergamon Press Ltd., Exeter, GB, (1995) 45(3):157-165.
Nair, H. et al., “Thrombo TraceX, a new diagnostic agent with high specificity to bind fibrin in vivo,”Blood Coagulation and Fibrinolysis(1998) 9(7):716-717.
Supplementary European Search Report dated Jul. 7, 2004 for International Application No. EP 98934690.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for detection of fibrin clots does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for detection of fibrin clots, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for detection of fibrin clots will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3484910

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.