Series of 5-[-(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone deriv

Details Series of 5-[-(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone deriv Series of 5-[-(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone deriv

1990-12-24

1992-02-04

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514826, A61K 3150

Patent

active

050860550

ABSTRACT:
A method of treating allergic disorders and pharmaceutical compositions therefore are disclosed for a series of 5-[(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone derivatives of Formula I. These compounds are useful in inhibiting Type I allergic ##STR1## responses in a living animal and thus can be used to treat allergic phenomena such as asthma, rhinitis, atopic dermatitis, chronic hives, allergic conjunctivitis and the like.

REFERENCES:
patent: 3419559 (1968-12-01), Lunsford et al.
patent: 3423418 (1969-01-01), Lunsford et al.
patent: 3455941 (1969-07-01), Lunsford et al.
patent: 3457267 (1969-07-01), Lunsford et al.
patent: 3513236 (1970-05-01), Lunsford et al.
patent: 4886794 (1989-12-01), Walsh

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