Stable spray-dried protein formulations

Details Stable spray-dried protein formulations Stable spray-dried protein formulations

2005-10-18

2005-10-18

Clardy, S. Mark (Department: 1616)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S489000, C424S499000, C514S951000, C514S970000, C514S975000

Reexamination Certificate

active

06956021

ABSTRACT:
Spray-dried particles having improved protein stability are produced by spray-drying a mixture including a protein, a phospholipid and an organic-aqueous co-solvent. Spray-dried particles which include at least 1 weight % phospholipid, having a tap density of less than 0.4 g/cm3can be prepared. The particles can be delivered to the pulmonary system of a patient.

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