Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2005-02-15
2005-02-15
Russel, Jeffrey Edwin (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S015800, C514S016700, C514S017400, C514S018700, C530S321000, C530S328000, C530S329000, C530S330000
Reexamination Certificate
active
06855692
ABSTRACT:
The invention relates to linear and cyclic peptide and pseudopeptide compounds useful as analgesics, pharmaceutical compositions comprising such compounds, the use of the compounds and the compositions in the treatment of pain, and commercial packages containing such compounds and compositions.
REFERENCES:
patent: 4416871 (1983-11-01), Walter et al.
patent: 4631270 (1986-12-01), Yankeelov, Jr. et al.
patent: 5169833 (1992-12-01), Hansen, Jr. et al.
patent: 5216124 (1993-06-01), Hansen, Jr. et al.
patent: 5364842 (1994-11-01), Justice et al.
patent: 5464821 (1995-11-01), Stig et al.
patent: 5470753 (1995-11-01), Stepetov et al.
patent: 5656267 (1997-08-01), Sagen et al.
patent: 5807828 (1998-09-01), Scarborough
patent: 5811391 (1998-09-01), Arrhenius et al.
patent: 5817750 (1998-10-01), Ruoslahti et al.
patent: 6566327 (2003-05-01), Lemaire
patent: 2097533 (1993-12-01), None
patent: WO9526362 (1995-10-01), None
patent: WO9606626 (1996-03-01), None
Abstract, Society for Neuroscience, vol. 23, Oct. 25-30, 1997. Peptide Receptors: Structure and Function p 674, Section 267.13.
Stacey Schultz-Cherry, “Regulation of Transforming Growth Factor-β Activation by Discrete Sequences of Thrombospondin 1”, vol. 270. No. 13. Issue of Mar. 31, 1995, pp. 7304-7310, J. Biol. Chem.
Richard S. Johnson, et al., “Novel Fragmentation Process of Peptides by Collision-Induced Decomposition in a Tandem Mass Spectrometer: Differentiation of Leucine and Isoleucine.”,Anal. Chem.1987, 59 pp. 2621-2625.
Thomas Hoeg-Jensen, Arno F. Spatola and Arne Holm, “Amino Monothio Acids in solid-phase Synthesis of Peptide Thioamides”,Int. J. Peptide ProteinRes. 47. 1996, pp 190-200.
Julie B. Seigan and Jacqueline Sagen., “A natural Peptide with NMDA inhibitory Activity reduces tonic pain in the Formalin Model.” vol. 8, No. 6. Apr. 14, 1997, pp. 1379-1381, Neuroreport.
Julie B. Siegan et al., “Suppression of Neuropathic Pain by a Naturally-derived Peptide with NMDA Antagonist Activity.”Brain Research755(1997) pp. 331-334.
Hama AT, Siegan JB, Herzberg U, Sagen J., “NMDA-induced spinal hypersensitivity is reduced by naturally derived peptide analog [Ser1]histogranin.”,Pharmacol Biochem BehavJan. 1999;62(1):67-74.
Maurice T, Privat A, Lemaire S., Corrigendum to ‘The pentadecapeptide [Ser1]histogranin impairs passive avoidance learning in mice’,Eur J Pharmacol, Dec. 12, 1995;287(2):219.Eur. J. Pharmacol.283 (1995) 251-4].
Maurice T, Privat A, Lemaire S., “The pentadecapeptide [Ser1]histogranin impairs passive avoidance learning in mice.”,Eur J Pharmacol,Sep. 5, 1995;283(1-3):251-4.
Lemaire S, Rogers C, Dumont M, Shukla VK, Lapierre C, Prasad J, Lemaire, I., “Histogranin, a modified histone H4 fragment endowed with N-methyl-D-aspartate antagonist and immunostimulatory activities.”,Life SciMar. 3, 1995;56(15):1233-41.
Prasad JA, Shukla VK, Lemaire S., “Synthesis and biological activity of histogranin and related peptides.”,Can J Physiol PharmacolFeb. 1995;73(2):209-14.
Shukla VK, Lemaire S, Dumont M, Merali Z., “N-methyl-D-aspartate receptor antagonist activity and phencyclidine-like behavioral effects of the pentadecapeptide, [Ser1]histogranin.”,Pharmacol Biochem BehavJan. 1995;50(1):49-54.
Lemaire I, Yang H, Cantin MF, Lemaire S., “Up-regulation of cytokine production in alveolar macrophages by histogranin, a novel endogenous pentadecapeptide.”,Immunol LettJun. 1994;41(1):37-42.
Dumot M, Prasad J, Lemaire S., “Interaction of histogranin and related peptides with [3H]dextromethorphan binding sites in rat brain.”,Neurosci Lett, May 23, 1994;173(1-2):135-8.
Rogers C, Lemaire S. J, “Characterization of [125I][Ser1]histogranin binding sites in rat brain.”,Pharmacol Exp TherOct. 1993;267(1):350-6.
Lemaire S, Griffiths J, Lapierre C, Lemaire I, Merali Z, Ravindran AV., “Characterization of histogranin receptors in human peripheral blood lymphocytes.”,Biochem Biophys Res CommunAug. 1, 1993;94(3): 1323-9.
Lemaire S, Shukla VK, Rogers C, Ibrahim IH, Lapierre C, Parent P, Dumont M., “Isolation and characterization of histogranin, a natural peptide with NMDA receptor antagonist activity.”,Eur. J PharmacolMay 15, 1993;245 (3):247-56.
Hong Ruan., Abstract of Dissertation submitted to The University of Ottawa for M.Sc. , “The antinociceptive effects of HN and related peptides in the mouse writhing and tailflck tests: the possible role of central D2 Receptor”, Aug., 1999.
Yamaki S. et al. High performance liquid chromatography of peptides on a microspherical carbon column;J. of chromatography A729:143-153 (1996).
Russel Jeffrey Edwin
University of Ottawa
LandOfFree
Histogranin peptides and their analgesic use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Histogranin peptides and their analgesic use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Histogranin peptides and their analgesic use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3480551