Hydroxyalkylamide derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

Reexamination Certificate

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Details

C546S226000, C564S080000, C564S134000, C564S138000, C564S142000, C514S488000, C514S330000, C514S602000

Reexamination Certificate

active

06965048

ABSTRACT:
The present invention relates to compounds of formula (I)wherein R1, R2, R3, R4, X, W, m and n are as defined hereinabove. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, parasite infections, gallstones, tumors and/or hyperproliferative disorders, and treatment and/or prophylaxis of impaired glucose tolerance and diabetes.

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Miao et al, Bioorg. Med. Chem. Lett., 13, pp. 1161-1164, 2003.
Moreno, A. et al, European Journal of Medicinal Chemistry, Editions Scientifique Elsevier, Paris, FR, vol. 39, No. 1, pp. 49-58 XP004492418 (2004).

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