Separation column devices and fabrication methods

Liquid purification or separation – With means to add treating material – Chromatography

Reexamination Certificate

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C210S656000, C422S070000, C422S105000, C073S061520

Reexamination Certificate

active

06923907

ABSTRACT:
Pressure-driven microfluidic separation devices, such as may be used for performing high performance liquid chromatography, are provided. Multiple separation columns may be defined in a single device and packed with stationary phase material retained by porous frits. One or more splitters may be provided to distribute slurry and/or mobile phase among multiple separation columns. In one embodiment, separation devices are substantially planar and fabricated with multiple device layers. Systems and methods employing slurry for packing separation devices are also provided.

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