Method of producing zero-order controlled-released devices

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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Details

424482, 424480, 424475, 427 3, A61K 914

Patent

active

050858661

ABSTRACT:
An improved method of producing a reservoir device having a rate-controlling membrane and zero-order (constant) release of an agent is provided. A core is sprayed with a solution having a polymer and a solvent, the solvent having a first component which is a rapidly evaporating, low-boiling-point first solvent and a slowly evaporating, high-boiling-point second solvent.

REFERENCES:
patent: 4572833 (1986-02-01), Pedersen et al.
patent: 4713243 (1987-12-01), Schiraldi et al.

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