Succinoylamino hydroxyethylamino sulfonyl urea derivatives...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S562000, C514S600000, C560S013000, C562S430000, C564S079000

Reexamination Certificate

active

06951886

ABSTRACT:
Succinoylamino hydroxyethylamino sulfonyl urea derivatives of the formula:wherein the substituents are as defined in the specification, are effective as retroviral protease inhibitors and in particular as inhibitors of HIV protease.

REFERENCES:
patent: 4450164 (1984-05-01), Bristol et al.
patent: 4477441 (1984-10-01), Boger et al.
patent: 4514391 (1985-04-01), Gordon et al.
patent: 4548926 (1985-10-01), Matsueda et al.
patent: 4599198 (1986-07-01), Hoover
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4668769 (1987-05-01), Hoover
patent: 4668770 (1987-05-01), Boger et al.
patent: 4757050 (1988-07-01), Natarajan et al.
patent: 4880938 (1989-11-01), Freidinger
patent: H725 (1990-01-01), Gordon
patent: 4963530 (1990-10-01), Hemmi et al.
patent: 4977277 (1990-12-01), Rosenberg et al.
patent: 5521219 (1996-05-01), Vazquez et al.
patent: 5578606 (1996-11-01), Vazquez et al.
patent: 5602119 (1997-02-01), Vazquez et al.
patent: 6515024 (2003-02-01), Vazquez et al.
patent: A-79823/87 (1988-04-01), None
patent: 104041 (1984-03-01), None
patent: 114993 (1984-08-01), None
patent: 172347 (1986-02-01), None
patent: 223437 (1987-05-01), None
patent: 0 264 795 (1988-04-01), None
patent: 337714 (1989-10-01), None
patent: 0 342 541 (1989-11-01), None
patent: 0 346 847 (1989-12-01), None
patent: 356223 (1990-02-01), None
patent: 389898 (1990-10-01), None
patent: 389898 (1990-10-01), None
patent: 393445 (1990-10-01), None
patent: 393457 (1990-10-01), None
patent: 402646 (1990-12-01), None
patent: 468641 (1992-01-01), None
patent: 2184730 (1987-07-01), None
patent: 2200115 (1988-07-01), None
patent: 2209752 (1989-05-01), None
patent: WO84/03044 (1984-08-01), None
patent: WO 92/00750 (1992-01-01), None
patent: 92/08699 (1992-05-01), None
Roberts et al, “Rational Design of Peptide-based Proteinase Inhibitors,” Science, 248, 358 (1990).
Erickson et al, “Design Activity, and 2.8Å Crystal Structure of a C2Symmetric Inhibitor Complexed to HIV-1 Protease,” Science, 249, 527 (1990).
Pearl et al, “Sequence specificity of retroviral proteases” Nature, 328, p. 482 (1987).
Martin, Drugs of the Future, 16(3), 210-212 (1991).
Meek et al,Letter To Nature, 343, 90-92 (1990).
McQudae et al,Science, 274, 454-456 (1990).
Rich et al, Peptide Inhibitors of Proteases, 511-520.
Rosenberg et al,J. Med. Chem., 30, 1224-1228 (1987).
Miller et al,Science, 246, 1149 (1989).
Pauwles et al,J. Virol Methods, 20, 309-321 (1988).
Bundgaard,Drugs Of The Future, 18(5), p. 443-458 (1991).
Futtkau,J. Prakt. Chem., 315, p. 1037 (1973).
Matier et. al.J. Med. Chem. 15, No. 5, p. 539 (1972).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Succinoylamino hydroxyethylamino sulfonyl urea derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Succinoylamino hydroxyethylamino sulfonyl urea derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Succinoylamino hydroxyethylamino sulfonyl urea derivatives... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3465176

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.