Hybridization of polynucleotides conjugated with...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S091200, C536S023100, C536S024300

Reexamination Certificate

active

06911310

ABSTRACT:
The present invention contemplates monitoring the amplification of nucleic acid using chromophore-containing polynucleotides having at least two donor chromophores operatively linked to the polynucleotide by linker arms, such that the chromophores are positioned by linkage along the length of the polynucleotide at a donor-donor transfer distance, and at least one fluorescing acceptor chromophore operatively linked to the polynucleotide by a linker arm, such that the fluorescing acceptor chromophore is positioned by linkage at a donor-acceptor transfer distance from at least one of the donor chromophores, to form a photonic structure for collecting photonic energy and transferring the energy to an acceptor chromophore, and methods using the photonic structures.

REFERENCES:
patent: 4822746 (1989-04-01), Walt
patent: 4868103 (1989-09-01), Stavrianopoulos et al.
patent: 4996143 (1991-02-01), Heller
patent: 5237515 (1993-08-01), Herron et al.
patent: 5322770 (1994-06-01), Gelfand
patent: 5332659 (1994-07-01), Kidwell
patent: 5405747 (1995-04-01), Jett et al.
patent: 5532129 (1996-07-01), Heller
patent: 5565322 (1996-10-01), Heller
patent: 5849489 (1998-12-01), Heller
patent: 6162603 (2000-12-01), Heller
patent: 0 229 943 (1987-07-01), None
Matthews et al, “Analytical Strategies for the use of DNA probes”, Anal. Biochem. (1988) 169:1-25.
Cardullo et al.,Proc. Natl. Acad. Sci. USA, 85:8790-8794 (1988).
Garner et al.,Anal. Chem., 62:2193-2198 (1990).
Glazer et al., “Emerging Techniques: Physofluor probes,”Trends in Biochemical Sciences 9(10):423 (1984).
Haddon et al.,Proc. Natl. Acad. Sci. USA, 92:1874-1878 (1985).
Heller et al.,Rapid Detection and Infection of Infectious Diseases, Kingsbury et al., Eds., Acad Pr. NY, pp. 245-256 (1985).
Hopfield et al.,Science 241:817-820 (1988).
Keller et al.,DNA Probes, pp. 104-108, Stockton Press, NY 1989).
Kornberg,DNA Synthesis(1974).
McAlear et al.,Molecular Electronic Devices II, Carter et al., Eds., Marcel Dekker, Inc., NY, pp. 623-633 (1987).
Morrison et al.,Anal. Biochem. 183:231-244 (1989).
Robinson et al.,Protein Eng., 1:295-300 (1987).
Tyagi et al., “Molecular Beacons: Probes That Fluoresce Upon Hybridization,”Nature Biotechnology, vol. 14 (1996).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hybridization of polynucleotides conjugated with... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hybridization of polynucleotides conjugated with..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hybridization of polynucleotides conjugated with... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3464103

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.