Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-05-03
2005-05-03
Mertz, Prema (Department: 1646)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S071100, C435S071200, C435S069700, C435S325000, C435S252300, C435S254110, C435S320100, C435S471000
Reexamination Certificate
active
06887683
ABSTRACT:
Two human G-Protein coupled receptor polypeptides and DNA (RNA) encoding each of such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides. Also disclosed are diagnostic methods for detecting a mutation in the nucleic acid sequence of each of the G-protein coupled receptors.
REFERENCES:
patent: 5585476 (1996-12-01), MacLennan et al.
patent: 5834587 (1998-11-01), Chan et al.
patent: 5912144 (1999-06-01), Au-Young et al.
patent: 6060272 (2000-05-01), Li et al.
patent: 20020052043 (2002-05-01), Li et al.
patent: WO 9115583 (1991-10-01), None
patent: WO 9412519 (1994-06-01), None
patent: WO 9848016 (1998-10-01), None
patent: WO 9935106 (1999-07-01), None
Mudroch, C. et al., Chemokine receptors and their role in inflammation and infectious diseases, Blood, vol. 95, No. 10, pp. 3032-3043, 2000.*
Watson, S. et al., The G-Protein Linked Receptor Facts Book, Academic Press, pp. 2-6 and 223-230, 1994.*
Reiger, R et al., Glossery of Genetics and Cytogenetics, Fourth edition, Springer-Verlag, Berlin, Heidelberg, New York, pp. 17-19, 1976.*
Chattaraj, S.C., “Cangrelor AstraZeneca,”Curr. Opin. Invest. Drugs 2:250-255, PharmaPress Ltd. (Feb. 2001).
Van Brocklyn, J.R., et al., “Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6,”Blood 95:2624-2629, The American Society of Hematology (Apr. 2000).
Wang, K., et al., “Blockade of the Platelet P2Y12Receptor by AR-C69931MX Sustains Coronary Artery Recanalization and Improves the Myocardial Tissue Perfusion in a Canine Thrombosis Model,”Arterioscler. Thromb. Vasc. Biol 22:357-362, Lippincott, Williams & Wilkins (Feb. 2003).
Database EMBL, Accession No. AA254425, Marra, M., et al., (first available Mar. 1997).
Partial European Search Report for European Application No. 03 01 5456, mailed Dec. 17, 2003, European Patent Office, Netherlands.
Copy of Co-Pending U.S. Appl. No. 09/518,381, Li et al., filed Mar. 3, 2000 (Not Published).
Lin, C.C. and Van de Sande, J.H., “Differential Fluorescent Staining of Human Chromosomes with Daunomycin and Adriamycin—the D-bands,”Science 190:61-63 (1975).
Nelson, P.S. et al., “An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones,”Genomics 47:12-25 (Jan. 1998).
NCBI Entrez, GenBank Accession No. D81412, Fujiwara, T. et al. (Feb. 1996).
NCBI Entrez, GenBank Accession No. AA274112, Marra, M. et al. (Mar. 1997).
NCBI Entrez, GenBank Accession No. AA353166, Adams, M.D. et al. (Apr. 1997).
NCBI Entrez, GenBank Accession No. AA810452, NCI-CGAP (Feb. 1998).
NCBI Entrez, GenBank Accession No. AA447306, Nelson, P.S. et al. (Apr. 1998).
NCBI Entrez, GenBank Accession No. AJ000479, Graeler, M.H. et al. (Nov. 1998).
NCBI Entrez, GenBank Accession No. CAA04118, Graeler, M.H. et al. (Nov. 1998).
NCBI Entrez, GenBank Accession No. CAA06847, Graeler, M.H. et al. (Nov. 1998).
Li Yi
Ruben Steven M.
Human Genome Sciences Inc.
Mertz Prema
Sterne Kessler Goldstein & Fox PLLC
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