Process for production of an antibiotic compound using Zalerion

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

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435 711, 435 712, 435171, 435254, 435911, C12P 2104, C12N 114, C12N 100

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active

051378132

ABSTRACT:
A process for producing an antibiotic compound which is normally one of several minor components in the cultivation of Z. arboricola ATCC 20868 to be the primary product is described.

REFERENCES:
patent: 4931352 (1990-06-01), Fromtling et al.
patent: 4968608 (1990-11-01), Giacobbe et al.
D. A. Hopwood, "Isolation of Mutants", Ch. VI, pp. 363-433, Methods in Microbiology, vol. 3A, Academic Press, 1970.
C. T. Calam, "Improvement of Microorganisms by Mutation, Hybridization & Selection" Ch. VII, pp. 435-459, Methods in Microbiology, vol. 3A, Academic Press, 1970.
R. E. Schwartz et al., J. Antibiotics 42, 163-167 (1989).
C. F. Wichmann et al., J. Antibiotics 42, 168,173 (1989).

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