Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-03-29
2005-03-29
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S358000, C435S377000
Reexamination Certificate
active
06872549
ABSTRACT:
The invention provides methods of increasing the production of polypeptides, optionally recombinant polypeptides, from mammalian cells using xanthine derivatives or hybrid polar compounds and cultures containing the same. Combinations of inducers including a hybrid polar compound and/or a xanthine derivative and/or an alkanoic acid can also be used, optionally at temperatures less than 37° C.
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Dell Bradley D.
McGrew Jeffrey T.
Trentalange Michael T.
Van Ness Kirk P.
Immunex Corporation
Ketter James
Sweeney Rosemary
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