Non-B, non-C, non-G hepatitis virus gene, polynucleotide,...

Details Non-B, non-C, non-G hepatitis virus gene, polynucleotide,... Non-B, non-C, non-G hepatitis virus gene, polynucleotide,...

2005-02-01

2005-02-01

Scheiner, Laurie (Department: 1648)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

C435S091320, C435S091330, C536S023720, C536S024300, C536S024320, C536S024330

Reexamination Certificate

active

06849431

ABSTRACT:
By isolating a so far unknown novel hepatitis virus and determining the gene sequence thereof, genes, polynucleotides, polypeptides, methods for isolating virus particles, virus particles, and antiviral antibodies, which can be used for diagnosis and treatment, as well as methods for detecting viruses are provided. Disclosed is a non-B, non-C, non-G hepatitis virus gene having a nucleotide sequence from which a sequence having a length of from about 3500 nucleotides to about 4000 nucleotides can be amplified by PCR utilizing an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 57 and an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 60 as primers, or PCR utilizing an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 57 and an oligonucleotide having the nucleotide sequence shown in SEQ ID NO: 61 as primers. Based on the nucleotide sequence of the gene, polypeptides etc. are provided.

REFERENCES:
patent: 0 339 668 (1989-11-01), None
patent: 09-299-078 (1997-11-01), None
patent: WO 9315111 (1993-08-01), None
Nishizawa, et al. “A Novel DNA Virus (TTV) Associated with Elevated Transaminase Levels in Posttransfusion hepatitis of Unknown Etiology,”Biochemical and Biophysical Research Communications, vol. 241, pp. 92-97, 1997.
Okamoto, et al. “Fecal Excretion of a Nonenveloped DNA Virus (TTV) Associated with Posttransfusion Non-A-G Hepatitis,”Journal of Medical Virology, vol. 56, pp. 128-132, 1998.
Okamoto, et al. “Molecular Cloning and Characterization of a Novel DNA Virus (TTV) Associated with Posttransfusion Hepatitis of Unknown Etiology,”Hepatology Research, vol. 10, pp. 1-16, 1998.
Simmonds, et al. “Detection of a Novel DNA Virus (TTV) in Blood Donors and Blood Products,”The Lancet, vol. 352, pp. 191-195, Jul. 18, 1998.
Takahashi, et al. “Partial—2.4-kb Sequences of TT Virus (TTV) Genome from Eight Japanese Isolates: Diagnostic and Phylogenetic Implications,”Hepatology Research, vol. 12, pp. 111-120, 1998.
International Search Report issued to a related, foreign patent application.
Okamoto, et al. “Molecular Cloning and Characterization of a Novel DNA Virus (TTV) Associated with Posttransfusion Hepatitis of Unknown Etiology,”Hepatology Research, vol. 10, pp. 1-16, 1998.
GENBANK nucleotide sequence AB008394 (Mar. 14, 1009).
Kuwada, et al. “Non-A, Non-B Fulminant Hepatitis is Also Non-E and Non-C,”The American Journal of Gastroenterology, vol. 89, No. 1, pp. 57-61, 1994.
Fiordalisi, et al. “High Prevalence of GB Virus C Infection in a Group of Italian Patients with Hepatitis of Unknown Etiology,”Journal of Infectious Diseases, vol. 174, No. 1, pp. 181-183, 1996.
Database EMBL Sequences, Accession No. B21160, Sep. 20, 1997.
Okamoto, et al.Virology, vol. 259, pp. 437-448, 1999.

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