Cost effective method for selective methylation of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S018500, C536S018600

Reexamination Certificate

active

06900296

ABSTRACT:
The invention relates to a cost effective and industrially advantageous process for the selective methylation of a hydroxy group at the 6 position of erythromycin A derivative which comprised methylating the erythromycin A derivative with a methylating agent in a mixture of toluene and a ploar aprotic solvent.

REFERENCES:
patent: 4331803 (1982-05-01), Watanabe et al.
patent: 4670549 (1987-06-01), Morimoto et al.
patent: 4672109 (1987-06-01), Watanabe et al.

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