Pseudorabies virus protein

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007920, C435S007940, C435S235100, C435S236000

Reexamination Certificate

active

06858385

ABSTRACT:
The present invention provides recombinant DNA molecules comprising a sequence encoding a pseudorabies virus (PRV) glycoprotein selected from the group consisting of gI, gp50, and gp63, host cells transformed by the recombinant DNA molecule sequences, the gI, gp50 and gp63 polypeptides. The present invention also provides subunit vaccines for PRV, methods for protecting animals against PRV infection and methods for distinguishing between infected and vaccinated animals.

REFERENCES:
patent: 4514497 (1985-04-01), Kit et al.
patent: 4609548 (1986-09-01), Kit et al.
patent: 4680176 (1987-07-01), Berns et al.
patent: 4703011 (1987-10-01), Kit et al.
patent: 4711850 (1987-12-01), Kit et al.
patent: 4810634 (1989-03-01), Post et al.
patent: 5047237 (1991-09-01), Cochran et al.
patent: 5352575 (1994-10-01), Petrovskis et al.
patent: 0 074 808 (1983-03-01), None
patent: 0 083 286 (1983-07-01), None
patent: 0 133 200 (1984-05-01), None
patent: 0 141 458 (1985-05-01), None
patent: 0 162 738 (1985-09-01), None
Tanaka et al (J. of Veterinary Medical Science vol. 56(6) pp 1177-1179), Dec. 1994.*
Stevely, Virus-Induced Proteins in Pseudorabies-Infected Cells,Virol., 16(5): 944-950 (Oct. 1975).
Todd, et al., Enzyme-Linked Immunosorbent-Assay for Detecting Antibodies to Aujeszky's Disease Virus in Pigs,The Veterinary Record, 109: 534-537 (Dec. 1981).
Robbins, et al., Construction ofE. coliExpression Plasmid Libraries Location of a Pseudorablies Virus Glycoprotein Gene,Journal of Molecular and Applied Genetics, 2: 485-496 (1984).
Pouwels, et al.,Cloning Vectors, A Laboratory Manual, Elsevier Science Publicaters B.V. (1985), selected pages relating to vectors forE. coli, fungi, yeasts, plant cells and animal cells (1985).
Gustafson, Pseudorables,Diseases of Swine, 5thed., pp. 209-223 (1981).
Jones and Hunt,Veterinary Pathology, 5thed., p. 322-326 (1983).
Aronson, ed.,Veterinary Pharmaceuticals&Biologicals, pp. 15/90, 15/98-99 (1983).
Ben-Porat and Kaolan, Synthesis of Proteins in Cells Infected with Herpesvirus, V. Viral Glycoproteins,Virology, 41: 265-73 (1970).
Kaplan and Ben-Porat, Synthesis of Proteins in Cells Infected with Herpesvirus, VI Characterization of the Proteins of the Viral Membrane,Proc. Natl. Acad. Sci., USA, 66: 799-806 (1970).
Wathen and Wathen, Isolation, Characterization, and Physical Mapping of a Pseudorabies Virus Mutant Containing Antigenically Altered gp50,J. Virol., 51: 57-62 (1984).
Hampl, et al., Characterization of the Envelope Proteins of Pseudorabies Virus.J. Virol., 52: 583-90 (1984).
Ben-Porat and Kaplan, Molecular Biology of Pseudorabies Virus, in B. Roizman ed.,The Herpesviruses, 3, pp. 105-173 (1984).
Rea et al., Mapping and Sequence of the Gene for the Pseudorabies Virus Glycoprotein which Accumulates in the Medium of Infected Cells,J. Virol., 54: 21-29 (1985).
Gielkens, et al., Genome Differences Among Field Isolates and Vaccine Strains of Pseudorables Virus,J. Gen. Virol., 66: 69-82 (1985).
Lomniczi, et al., Deletions in the Genomes of Pseudorables Virus Vaccine Strains and Existence of Four Isomers of the Genomes,J. Virol., 49: 970-79 (1984).
Mettenleiter, et al., Mapping of the Structural Gene of Pseudorables Virus Glycoprotein A and Identification of Two Non-Glycosylated Precursor Polypeptides, J. Virol., 53: 52-57 (1985).
Robbins, et al., Localization of a Pseudorables Virus Glycoprotein Gene Using anE. coliExpression Plasmid Library,Herpesvirus, pp. 551-561 (1984).
Mettenleiter et al., Pseudorables Virus Avirulent Strains Fail to Express a Major Glycoprotein,Journal of Virology, 56: 307-311 (1985).
Khristova, et al., Thymidine Kinase Activity of Virulent and Vaccinal Strains of Aujezsky's Disease Virus,Veterinary Science, XXII(3): 15-22.
Tatrov, Apathogenic Mutant of the Aujeszky Virus Induced by 5-Iodo-2-Deoxyuridine (IUDR),Zentralblatt Veterinarmedizin, 15: 847-53 (1968).
Randall, et al., Glycoproteins with Type Common and Type Specific Antigenic Sites Excreted from Cells Infected with Herpes Simplex Virus Types 1 and 2,J. Gen. Virol., 48: 297-310 (1980).
Gielkens, et al., Genome Differences Among Field Isolates and Vaccine Strains of Pseudorables Virus,J. Gen. Virol., 66: 69-82 (1985).
Valenzuela, et al., Antigen Engineering in Yeast: Synthesis and Assembly of Hybrid Hepatitis B Surface Antigen-Herpes Simplex 1 gD Particles,Bio/Technology3: 323-36 (1985).
Kieny, et al., Expression of Rabies Virus Glycoprotein From a Recombinant Vaccinia Virus,Nature, 312: 163-66 (1984).
Holland, et al., Antigenic Variants of Herpes Simplex Virus Selected with Glycoprotein-Specific Monoclonal Antibodies,J. Virology, 45(2):672-82 (1983).
Post, and Roizman, A Generalized Technique for Deletion of Specific Genes in Large Genomes: α Gene 22 of Herpes Simplex Virus 1 is Not Essential for Growth,Cell, 25: 227-32 (1981).
Todd, and McFerran, Control of Aujeszky's Disease,The Veterinary Record, 117(24); 647 (1985).
Thomsen, et al., Replication and Virulence of Pseudorables Virus Mutants Lacking Glycoprotein gX,J. Virology, 61(1):229-32 (1987).
Sandri-Goldin, et al., Method for Induction of Mutations in Physically Defined Regions of the Herpes Simplex Virus Genome,J. Virology, 38(1): 41-49 (1981).
Quint, et al., Construction and Characterization of Deletion Mutants of Pseudorabies Virus: A New Generation of‘Live’ Vaccines,J. Gen. Virol., 68: 523-34 (1987).
Roizman et al., Genetic Engineering of Novel Genomes of Large DNA Viruses,Science, 229: 1208-14 (Sep. 1985).
Marchioli et al., A Vaccine Strain of Pseudorabies Virus with Deletions in the Thymidine Kinase and Glycoprotein X Genes Am J. Vet. Res., 481(11): 1577-83 (1987).
Davison et al., Chapter 7, pp. 103-124, inRecombinant DNA Research and Viruses, Becker, et. 1985.
Robbins et al., Pseudiorabies Virus Gene Encoding Glycoprotein GIII is not Essential for Growth in Tissue Culture,J. Virol., 59(3) 635-49, (Sep. 1986).
Wathen et al., Production and Characterization of Monoclonal Antibodies Directed Against Pseudorabies Virus, Virus Research, 4: 19-29 (1985).
Norid and Vestergaard., Immunoelectrophoretic Identification and Purification of Herpes Simplex Virus Antigens Released from Infected Cells in Tissue Culture,Intervirology11: 104-10 (1979).
Watson et al., Herpes Simplex Virus Type-1 Glycoprotein D. Gene: Nucleotide Sequence and Expression inEscherichia coli, Science218(4570): 381-4 (Oct. 22, 1982).
Young et al., Dissection of Mycobacterium Tuberculosis Antigens Using Recombinant DNA,Proc Natl Acad Sci USA, 82(9): 2583-7, (May 1985).
Gingeras et al., Nucleotide Sequences From The Adenovirus-2 Genome,J. Biol Chem, 257(22): 13475-91 (Nov. 25, 1982).
Galibert et al., Nucleotide Sequence of a Cloned Woodchuck Hepatitis Virus Genome: Comparison with the Hepatitis B Virus Sequence,J. Virol, 41(1): 51-65 (Jan. 1982).
Lenardo et al., Characterization of the Genes Specifying Two Metacyclic Variable Antigen Types in Trypanosoma brucei Rhodesiense,Proc Natl Acad Sci USA, 81(21): 6642-6 (Nov. 1984).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pseudorabies virus protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pseudorabies virus protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pseudorabies virus protein will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3444455

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.