Carbamoyl tetrahydropyridine derivatives

Details Carbamoyl tetrahydropyridine derivatives Carbamoyl tetrahydropyridine derivatives

2005-05-17

2005-05-17

Berch, Mark (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S323000

Reexamination Certificate

active

06894168

ABSTRACT:
Carbamoyl tetrahydropyridine derivatives represented by the formula:[in the formula, R1and R2are identical or different, and each represents a hydrogen atom, a C1-C5alkyl group, or the like; Y1—Y2represents (R4)C═C(R5), (R6)C═N, N═N, (R7) N—CO, or N═C(R8); X1, X2, and X3are identical or different, and each represents a hydrogen atom, a halogen atom, or the like; R3, R4, R5, and R6are identical or different, and each represents a hydrogen atom or an alkyl group; R7represents a hydrogen atom, a C1-C5alkyl group, or the like; and R8represents a hydrogen atom or a carbamoyl group] or a pharmaceutically acceptable salt thereof, and intermediates for the preparation thereof are provided.The derivatives described above are effective for diseases which are believed to involve CRF.

REFERENCES:
patent: 4229453 (1980-10-01), Roth et al.
patent: 0 976 745 (1998-03-01), None
patent: 11-335376 (1999-12-01), None
patent: 2000-86663 (2000-03-01), None
patent: 9413676 (1994-06-01), None
Lasslo et al. {Journal of Organic Chemistry (1957), 22, 837-9}.*
Biochemical Pharmacology, vol. 37, No. 19, pp. 3749-3753, 1998.
Tetrahedron Letters, vol. 26, No. 9, pp. 1229-1232, 1985.

Affiliated with

Also associated with

Rating

Carbamoyl tetrahydropyridine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carbamoyl tetrahydropyridine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carbamoyl tetrahydropyridine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3444265