Suppression of cross-reactivity and non-specific binding by...

Details Suppression of cross-reactivity and non-specific binding by... Suppression of cross-reactivity and non-specific binding by...

2005-03-01

2005-03-01

Housel, James (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S005000, C435S006120, C435S007100, C435S007200, C435S007920, C435S068100, C435S069100, C435S069700, C435S328000, C435S252330, C530S350000

Reexamination Certificate

active

06861231

ABSTRACT:
The structure, formation and use of blocked antibodies, especially those blocked with Protein A, or active fragments of Protein A, are disclosed as well as processes of producing such antibodies. The uses of such blocked antibodies to achieve significant reduction in both specific cross-reaction and non-specific interaction thereby increasing specificity and reactivity with targeted antigenic sites is also described.

REFERENCES:
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 5476786 (1995-12-01), Huston
patent: 5561045 (1996-10-01), Dorval et al.
patent: 5665539 (1997-09-01), Sano et al.
patent: 6087476 (2000-07-01), Kenten et al.

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