Method for stabilizing extra-chromosomal elements in bacteria du

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435223, 435233, 43525231, 43525233, 435320, 435 694, C12P 2100, C12N 1500, C12N 990, C12N 120

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049200488

ABSTRACT:
A method for stabilization of extra-chromosomal elements in bacteria during cultivation which comprises transformation of a host bacterium having a defect in a chromosomal gene needed for the synthesis or maintenance of the cell envelope with an extra-chromosomal element capable of complementing the chromosomal gene defect of the host bacterium, the extra-chromosomal element also including an expressible DNA-sequence coding for a desired product.

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