Hepatitis A virus nucleotide sequences, recombinant proteins...

Details Hepatitis A virus nucleotide sequences, recombinant proteins... Hepatitis A virus nucleotide sequences, recombinant proteins...

2005-09-13

2005-09-13

Scheiner, Laurie (Department: 1648)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C435S006120, C536S023100, C536S023720

Reexamination Certificate

active

06942965

ABSTRACT:
Hepatitis A virus primers and probes derived from the capsid proteins and junction between the capsid precursor P1 and 2A of the HAV genome are disclosed. Also disclosed are nucleic acid-based assays using the primers and probes, antigen detection of HAV, and immunoassay for detecting the antibodies that bind to HAV.

REFERENCES:
patent: 5516630 (1996-05-01), Ticehurst et al.
Cohen et al., “Complete Nucleotide Sequence of Wild-Type Hepatitis A Virus: Comparison with Different Strains of Hepatitis A Virus and Other Picomaviruses,”J. Virology61(1):50-59, 1987.
Locarnini et al., “Restricted replication of human hepatitis A virus in cell Culture: intracellular biochemical studies,”J. Virol.37:216-225, 1981.
Siegl et al., “The physicochemical properties of infectious hepatitis A virions,”J. Gen. Virol.57:331-341, 1981.

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