Peptidase-cleavable, targeted antineoplastic drugs and their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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C514S016700, C514S017400, C514S018700, C514S034000, C530S322000, C530S328000, C530S329000, C530S330000, C536S006400

Reexamination Certificate

active

06844318

ABSTRACT:
This invention is directed to antineoplastic agents conjugated to enzyme-cleavable peptides comprising the amino acid recognition sequence of a membrane-bound and/or cell-secreted peptidase, and to the use of such conjugated compounds as chemotherapeutic agents in the targeted treatment of cancers.

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