Thermostable UvrA and UvrB polypeptides and methods of use

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S015000, C435S183000, C435S194000, C530S350000, C536S023100, C536S023200

Reexamination Certificate

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06921641

ABSTRACT:
The present invention provides thermostabile UvrA polypeptides, thermostable UvrB polypeptides and the polynucleotides that encode the UvrA and UvrB polypeptides. The invention also includes compositions and kits containing the UvrA and UvrB polypeptides of the present invention. Also provided by the present invention are methods of detecting DNA damage using the UvrA and UvrB polypeptides.

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